P0037
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P0037
Sigma
PP242 hydrate 
≥98% (HPLC), powder
| Synonym: | 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol |
| Linear Formula: | C16H16N6O · xH2O |
| Molecular Weight: | 308.34 (anhydrous basis) |
Description
| Biochem/physiol Actions | PP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR. |
Properties
| assay | ≥98% (HPLC) |
| form | powder |
| color | off-white |
| solubility | DMSO: >10 mg/mL |
| storage temp. | 2-8°C |
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 2 |
References
| reference | Apsel, B., et al., Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nature Chem. Biol. 4, 691-699, (2008) |
